Description

Bufetolol is a selective β-adrenergic receptor antagonist (β-blocker) with the CAS registry number 53684-49-4. This compound is of significant interest in pharmaceutical research and development for its potential cardiovascular applications. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, preclinical studies, and analytical method development.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of advanced β-blocker drug candidates.
• Biochemical Research: Used as a reference standard or active agent in studies investigating adrenergic receptor mechanisms and cardiovascular pharmacology.
• Analytical Standard: Serves as a high-purity standard for quality control (QC) and assurance (QA) in HPLC, LC-MS, and other chromatographic methods.
• Preclinical Development: Employed in vitro and in vivo studies to evaluate pharmacokinetics, metabolism, and efficacy profiles.

Basic Information

Item	Detail
Product Name	Bufetolol
CAS No.	53684-49-4
Molecular Formula	C16H25NO3
Molecular Weight	279.38 g/mol
Synonyms	1-(tert-Butylamino)-3-[2-(cyclopropylmethoxy)phenoxy]-2-propanol; Bufetolol Hydrochloride (salt form); (±)-Bufetolol; DL-Bufetolol; BUF-101; Bunitrolol analog; Adrenergic β-Antagonist Bufetolol; 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[2-(cyclopropylmethoxy)phenoxy]-
EINECS	Contact for details

Quality Control

Our Bufetolol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and control of specified impurities to ensure it meets high-grade research standards. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.