Description

Synalar-C is a high-purity synthetic corticosteroid compound, widely recognized for its potent anti-inflammatory and antipruritic properties. This active pharmaceutical ingredient (API) is essential for formulators requiring reliable and consistent performance in topical pharmaceutical preparations. It is primarily utilized by manufacturers in the pharmaceutical and dermatological sectors for developing creams, ointments, and lotions aimed at treating various skin conditions.

Application

• Topical Corticosteroid Formulations: Primary active ingredient in prescription-strength creams, ointments, and gels for treating eczema, psoriasis, and dermatitis.
• Dermatological Preparations: Used in compounding pharmacies for customized topical solutions targeting severe inflammation and itching.
• Veterinary Medicine: Incorporated into topical treatments for inflammatory skin conditions in animals.
• Research & Development: Serves as a reference standard and key intermediate in pharmaceutical R&D for novel anti-inflammatory agents.

Basic Information

Product Name	Synalar-C
CAS No.	53262-68-3
Molecular Formula	C₂₄H₃₂FO₅
Molecular Weight	416.51 g/mol
Synonyms	Fluocinolone Acetonide Acetate; 6α,9α-Difluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione Cyclic 16,17-Acetal with Acetone 21-Acetate; Fluocinolone Acetonide 21-Acetate; Fluocinolone Acetonide Acetic Ester; RS-2252; Synalar-C; Fluocinoloni Acetonidi Acetas; Fluocinolonacetonidacetat
EINECS	Contact for details

Quality Control

Our Synalar-C is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical applications. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) documenting full compliance with in-house specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.