Description

Pregna-1,4-Diene-3,20-Dione, 21-(Acetyloxy)-9-Bromo-11-Hydroxy-16-Methyl-17-(1-Oxopropoxy)-, (11β,16β)- (9Ci) is a high-purity synthetic steroid derivative, recognized for its complex molecular architecture and significant role as a key pharmaceutical intermediate. This compound is valued for its precise structural features, which are critical for the development and synthesis of advanced active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within the fields of endocrinology and anti-inflammatory research.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of potent corticosteroid APIs and other specialized steroid-based therapeutics.
• Research & Development: Used in academic and industrial R&D laboratories for studying structure-activity relationships (SAR) and developing new drug candidates.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development, validation, and impurity profiling.
• Process Chemistry: Integral to process development and scale-up activities for the commercial manufacturing of steroid drugs.
• Biochemical Research: Utilized in studies investigating steroid hormone receptor interactions and metabolic pathways.

Basic Information

Product Name	Pregna-1,4-Diene-3,20-Dione, 21-(Acetyloxy)-9-Bromo-11-Hydroxy-16-Methyl-17-(1-Oxopropoxy)-, (11β,16β)- (9Ci)
CAS No.	52092-15-6
Molecular Formula	C₂₇H₃₅BrO₇
Molecular Weight	551.47 g/mol
Synonyms	9-Bromo-11β,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-acetate 17-propionate; 9α-Bromo-11β,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-acetate 17-propionate; 9-Bromobetamethasone 21-acetate 17-propionate; (11β,16β)-9-Bromo-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione 21-acetate 17-propionate; 9-Bromo-16β-methylprednisolone 21-acetate 17-propionate
EINECS	Contact for details

Quality Control

Our Pregna-1,4-Diene-3,20-Dione, 21-(Acetyloxy)-9-Bromo-11-Hydroxy-16-Methyl-17-(1-Oxopropoxy)-, (11β,16β)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and opened under moisture-controlled conditions when necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.