Description

(11β,16β)-9-Bromo-11-Hydroxy-16-Methyl-17,21-Bis(1-Oxopropoxy)Pregna-1,4-Diene-3,20-Dione is a high-purity synthetic steroid derivative, specifically a halogenated and esterified pregnane compound. It serves as a critical advanced pharmaceutical intermediate for the research and development of novel therapeutic agents, particularly in the fields of endocrinology and anti-inflammatory drug discovery. This compound is essential for pharmaceutical R&D laboratories and fine chemical manufacturers requiring precise, structurally complex building blocks for synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel corticosteroid analogs and other potent steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies to develop new drugs targeting inflammatory pathways and hormonal receptors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis using HPLC, LC-MS, or NMR.
• Biochemical Research: Employed in academic and industrial research to study steroid metabolism, receptor binding, and the biochemical effects of halogenated steroid structures.
• Process Chemistry: Utilized in scaling up synthetic routes for the production of experimental drug candidates during preclinical and clinical development phases.

Basic Information

Item	Details
Product Name	(11β,16β)-9-Bromo-11-Hydroxy-16-Methyl-17,21-Bis(1-Oxopropoxy)Pregna-1,4-Diene-3,20-Dione
CAS No.	52092-14-5
Molecular Formula	C₂₈H₃₇BrO₇
Molecular Weight	565.50 g/mol
Synonyms	9-Bromo-11β,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate; 9-Bromo-11β-hydroxy-16β-methyl-17α,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione; 9-Bromobetamethasone 17,21-dipropionate; Halogenated Betamethasone Dipropionate Derivative; (11β,16β)-9-Bromo-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate
EINECS	Contact for details

Quality Control

Our (11β,16β)-9-Bromo-11-Hydroxy-16-Methyl-17,21-Bis(1-Oxopropoxy)Pregna-1,4-Diene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure compliance with ICH guidelines. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere in a freezer (-20°C).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Maximum Unknown Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.