Description

[R(R*,R*]-2-Amino-1-[p-(Methylsulphonyl)Phenyl]Propane-1,3-Diol is a high-purity chiral amino diol derivative, distinguished by its methylsulfonylphenyl functional group. This compound is valued for its role as a critical chiral intermediate and building block in sophisticated organic synthesis. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug research.
• Asymmetric Synthesis: Serves as a chiral auxiliary or resolving agent for the production of enantiomerically pure compounds.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for catalytic asymmetric transformations.
• Fine Chemical Production: Employed as a building block for advanced materials and specialty chemicals requiring specific stereochemistry.
• Academic and Industrial Research: A valuable compound for methodological studies in synthetic organic and medicinal chemistry.

Basic Information

Product Name	[R(R*,R*]-2-Amino-1-[p-(Methylsulphonyl)Phenyl]Propane-1,3-Diol
CAS No.	51458-28-7
Molecular Formula	C10H15NO4S
Molecular Weight	245.30 g/mol
Synonyms	(1R,2S)-2-Amino-1-(4-methylsulfonylphenyl)propane-1,3-diol; (R,R)-P-Methylsulfonyl Phenyl Amino Diol; 1,3-Propanediol, 2-amino-1-[4-(methylsulfonyl)phenyl]-, (1R,2S)-rel-; 2-Amino-1-(4-methanesulfonylphenyl)propane-1,3-diol; Amino Diol Sulfone Derivative; Chiral Amino Diol Intermediate; CAS 51458-28-7
EINECS	Contact for details

Quality Control

Our production of [R(R*,R*]-2-Amino-1-[p-(Methylsulphonyl)Phenyl]Propane-1,3-Diol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting customer and research-grade specifications. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.