Description

2,5-Bis(Trifluoromethyl)Benzonitrile is a high-value, multi-functional fluorinated aromatic building block. Its unique structure, featuring two electron-withdrawing trifluoromethyl groups and a reactive nitrile, makes it an essential intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs). This compound is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in areas requiring fluorinated motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl groups can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to better performance and stability in electronic displays.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart unique properties such as chemical resistance, low surface energy, and thermal stability.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to create novel ligands and catalysts for asymmetric synthesis and other catalytic processes.
• Advanced Material Research: Acts as a building block in materials science for developing fluorinated porous materials, coatings, and other functional materials.

Basic Information

Product Name	2,5-Bis(Trifluoromethyl)Benzonitrile
CAS No.	51012-27-2
Molecular Formula	C10H3F6N
Molecular Weight	239.13 g/mol
Synonyms	2,5-Bis(trifluoromethyl)benzonitrile; 2,5-Bis(trifluoromethyl)phenyl cyanide; 2,5-Di(trifluoromethyl)benzonitrile; Benzonitrile, 2,5-bis(trifluoromethyl)-; α,α,α,α',α',α'-Hexafluoro-2,5-xylyl cyanide; 2,5-Bis(trifluoromethyl)benzene carbonitrile; 2,5-Bis(trifluoromethyl)cyanobenzene; 2,5-Di(trifluoromethyl)cyanobenzene
EINECS	Contact for details

Quality Control

Our 2,5-Bis(Trifluoromethyl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.