Description

[[4-[2-Hydroxy-3-(Isopropylamino)Propoxy]Phenyl]Methyl]Urea is a high-purity organic compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical intermediate or active pharmaceutical ingredient (API) in the synthesis of targeted therapeutics. It is primarily required by pharmaceutical manufacturers and R&D institutions focused on developing novel cardiovascular and metabolic disease treatments. Our supply ensures the stringent quality and batch-to-batch consistency demanded for preclinical and clinical-stage applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of β-adrenergic blocking agents (β-blockers).
• Active Pharmaceutical Ingredient (API): Used in the formulation of specific cardioselective medications.
• Biochemical Research: Serves as a reference standard and tool compound in pharmacological studies targeting adrenergic receptors.
• Process Development: Employed in scaling up and optimizing synthetic routes for new chemical entities (NCEs).
• Metabolite Synthesis: Used to prepare labeled or unlabeled metabolites for pharmacokinetic and metabolic profiling studies.

Basic Information

Product Name	[[4-[2-Hydroxy-3-(Isopropylamino)Propoxy]Phenyl]Methyl]Urea
CAS No.	50992-77-3
Molecular Formula	C14H23N3O3
Molecular Weight	281.35 g/mol
Synonyms	Celiprolol Impurity; Celiprolol Related Compound; 1-[[4-[2-Hydroxy-3-[(1-Methylethyl)amino]propoxy]phenyl]methyl]urea; Urea, N-[[4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]methyl]-; N-((4-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)methyl)urea; Celiprolol EP Impurity B; Celiprolol Hydrochloride Impurity
EINECS	Contact for details

Quality Control

Our [[4-[2-Hydroxy-3-(Isopropylamino)Propoxy]Phenyl]Methyl]Urea is manufactured under a strict quality management system to meet the exacting standards of pharmaceutical applications. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to support regulatory filings (e.g., ICH Q3A, USP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.