Description

Carubicin is a potent anthracycline antibiotic and antineoplastic agent. This compound is of significant interest in pharmaceutical research and development due to its structural similarity to other clinically important chemotherapeutic agents like doxorubicin. It is primarily utilized by research institutions, pharmaceutical manufacturers, and biotechnology companies engaged in oncology drug discovery, mechanism of action studies, and the synthesis of novel therapeutic derivatives.

Application

• Pharmaceutical Intermediate: Serves as a key starting material or intermediate in the synthesis of novel anthracycline-based chemotherapeutic agents.
• Biomedical Research: Used in laboratory studies to investigate the mechanisms of action, resistance, and cytotoxicity of anthracycline antibiotics.
• Reference Standard: Employed as an analytical standard in quality control (QC) and research & development (R&D) laboratories for method development and validation.
• Oncology Drug Discovery: A critical compound for structure-activity relationship (SAR) studies aimed at developing new anticancer drugs with improved efficacy and reduced side effects.
• Biochemical Studies: Utilized in studies exploring DNA intercalation, topoisomerase II inhibition, and free radical generation.

Basic Information

Product Name	Carubicin
CAS No.	50935-04-1
Molecular Formula	C26H27NO10
Molecular Weight	513.49 g/mol
Synonyms	Carminomycin I; 4-Demethoxy-13-dihydrodaunorubicin; 11-Deoxycarminomycin; (8S,10S)-8-Acetyl-10-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione; NSC-180024; Antibiotic MA 144 T1
EINECS	Contact for details

Quality Control

Our Carubicin is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR) and purity assessment by HPLC, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing specific batch results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be kept under inert atmosphere or in a desiccator for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	Red to orange-red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.