Description

Deacylcortivazol 21-Mesylate is a synthetic corticosteroid derivative, specifically a mesylate salt form, known for its potent glucocorticoid receptor activity. This high-purity compound is critical for pharmaceutical research and development, particularly in the study of steroid hormone action and anti-inflammatory mechanisms. It serves as a key intermediate and reference standard for researchers and manufacturers in the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control and analytical method development in steroid-based drug manufacturing.
• Biochemical Research: A vital tool for in vitro and in vivo studies investigating glucocorticoid receptor (GR) binding, signaling pathways, and gene expression regulation.
• Drug Discovery & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) precursor in the synthesis of novel corticosteroid therapeutics.
• Mechanistic Studies: Employed to explore the anti-inflammatory and immunosuppressive effects of corticosteroids at a molecular level.
• Academic Research: Utilized in university and institutional labs for fundamental endocrinology and pharmacology research.

Basic Information

Product Name	Deacylcortivazol 21-Mesylate
CAS No.	50630-90-5
Molecular Formula	C26H33NO7S
Molecular Weight	503.61 g/mol
Synonyms	Deacylcortivazol 21-Methanesulfonate; 11β,17α,21-Trihydroxy-6,16α-dimethyl-2'-phenyl-2'H-pregna-2,4,6-trieno[3,2-c]pyrazol-20-one 21-Methanesulfonate; 21-Deacylcortivazol Mesylate; Cortivazol 21-Mesylate Derivative; NSC 100880; SQ 15102; U-82207
EINECS	Contact for details

Quality Control

Our Deacylcortivazol 21-Mesylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.