Description

17-o-Acetyl Diflorasone is a synthetic corticosteroid derivative, specifically an acetylated form of diflorasone. This compound is a crucial pharmaceutical intermediate, valued for its role in the synthesis of advanced topical corticosteroids with potent anti-inflammatory and antipruritic properties. It is primarily required by manufacturers in the pharmaceutical and fine chemical sectors for the development and production of specialized dermatological treatments.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of high-potency topical corticosteroids like diflorasone diacetate.
• Active Pharmaceutical Ingredient (API) Development: Used in research and development for creating new steroid-based drug candidates.
• Dermatological Preparations: Serves as a precursor in the manufacture of creams, ointments, and lotions for treating psoriasis, eczema, and dermatitis.
• Veterinary Medicine: Potential use in formulating anti-inflammatory treatments for animal skin conditions.
• Biochemical Research: Utilized in laboratory studies to investigate glucocorticoid receptor activity and steroid metabolism pathways.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical testing in pharmaceutical labs.

Basic Information

Product Name	17-o-Acetyl Diflorasone
CAS No.	50630-19-8
Molecular Formula	C24H30F2O6
Molecular Weight	452.49 g/mol
Synonyms	Diflorasone 17-Acetate; 6α,9α-Difluoro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-Acetate; 17α-Acetoxy-6α,9α-difluoro-11β,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione; 17-Acetyl-6α,9α-difluoro-11β,21-dihydroxy-16β-methyl-1,4-pregnadiene-3,20-dione; NSC 121055; 17-O-Acetyldiflorasone
EINECS	Contact for details

Quality Control

Our 17-o-Acetyl Diflorasone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-grade pharmaceutical intermediate specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and compliance with your quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.