Description

1H-Benzimidazole, 4-Fluoro- is a high-purity fluorinated heterocyclic building block of significant commercial and research interest. Its core value lies in its role as a versatile intermediate for synthesizing advanced pharmaceutical compounds and functional materials. This product is essential for R&D chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate the benzimidazole scaffold with fluorine substitution for enhanced biological activity and material properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and anti-parasitic drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced fungicides and pesticides, where the fluorine atom can improve metabolic stability and bioavailability.
• Material Science Research: Serves as a precursor for organic electronic materials, including ligands for metal-organic frameworks (MOFs) and components for organic light-emitting diodes (OLEDs).
• Chemical Biology & Proteomics: Employed as a building block for designing enzyme inhibitors, fluorescent probes, and other biochemical tools.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	1H-Benzimidazole, 4-Fluoro-
CAS No.	5847-89-2
Molecular Formula	C7H5FN2
Molecular Weight	136.13 g/mol
Synonyms	4-Fluorobenzimidazole; 4-Fluoro-1H-benzimidazole; 4-Fluoro-1H-benzo[d]imidazole; 4-F-BIM; 4-Fluorobenzimidazole; 4-Fluorobenzoimidazole; 4-Fluoro-1H-benzimidazole; 1H-Benzimidazole, 4-fluoro-
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazole, 4-Fluoro- is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.