Description

4,4,4-Tris(Trifluoromethyl)Butanenitrile is a high-value, fluorinated organic nitrile building block characterized by its unique trifluoromethyl groups. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its fluorine content imparts desirable properties like enhanced stability and lipophilicity. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with tailored performance characteristics.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of fluorinated drug candidates, potentially for central nervous system (CNS) agents, anti-inflammatory drugs, and antiviral medications.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms can improve biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated components in electronic display materials, contributing to improved dielectric anisotropy and thermal stability.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, enhancing properties such as chemical resistance, low surface energy, and optical clarity.
• Organic Synthesis Building Block: A versatile reagent for constructing complex molecular architectures via reactions at the nitrile group, useful in academic and industrial research.
• Fluorinated Surfactant Precursor: Can be utilized in the synthesis of specialty surfactants and surface treatment agents for demanding industrial applications.

Basic Information

Item	Details
Product Name	4,4,4-Tris(Trifluoromethyl)Butanenitrile
CAS No.	5634-47-9
Molecular Formula	C7H4F9N
Molecular Weight	261.10 g/mol
Synonyms	4,4,4-Tris(trifluoromethyl)butyronitrile; Perfluoro-tert-butylacetonitrile; 1,1,1,4,4,4-Hexafluoro-2-(trifluoromethyl)butanenitrile; 3,3,3-Trifluoro-2-(trifluoromethyl)-2-(trifluoromethyl)propanenitrile; (Perfluoro-tert-butyl)acetonitrile; TFBN (common abbreviation); Pentafluoro-2-(trifluoromethyl)butanenitrile (alternate notation)
EINECS	Contact for details

Quality Control

Our 4,4,4-Tris(Trifluoromethyl)Butanenitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We are committed to meeting the stringent requirements for cGMP intermediates and REACH compliance for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. The container should be kept tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.