Description

12,12-(Ethylenebisoxy)-5α-Pregnan-20-One is a high-purity, synthetic steroid derivative with a unique ethylene ketal modification at the 12-position. This specialized chemical intermediate is valued for its defined structure and purity, enabling precise synthesis in advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the production of novel therapeutic agents and reference standards.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroid-based pharmaceuticals and active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic candidates.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in laboratory settings.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of complex steroid molecules.
• Biochemical Research: Used as a tool compound to study steroid hormone pathways and receptor interactions.

Basic Information

Product Name	12,12-(Ethylenebisoxy)-5α-Pregnan-20-One
CAS No.	5618-27-9
Molecular Formula	C₂₄H₃₈O₃
Molecular Weight	374.56 g/mol
Synonyms	5α-Pregnan-20-one, 12,12-(ethylenedioxy)-; 12,12-Ethylenedioxy-5α-pregnan-20-one; 12,12-Ethylenedioxypregnan-20-one; 5α-Pregnan-20-one, 12,12-(ethylenebisoxy)-; 12,12-(Ethylenedioxy)pregnan-20-one; 12,12-Ethylenedioxy-5α-pregnane-20-one
EINECS	Contact for details

Quality Control

Our 12,12-(Ethylenebisoxy)-5α-Pregnan-20-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.