Description

Triamcinolone Hexacetonide is a potent, long-acting synthetic corticosteroid ester. This compound is valued for its pronounced anti-inflammatory and immunosuppressive properties, making it a critical active pharmaceutical ingredient (API) for targeted therapeutic formulations. It is primarily required by pharmaceutical manufacturers and research institutions developing injectable suspensions for the treatment of inflammatory joint conditions, dermatological disorders, and ophthalmic applications.

Application

• Pharmaceutical API: Primary use as the active ingredient in long-acting injectable corticosteroid formulations.
• Intra-articular Injections: For the management of inflammation and pain in conditions like rheumatoid arthritis, osteoarthritis, and bursitis.
• Dermatological Preparations: Used in creams, ointments, or intralesional injections for treating severe skin conditions such as psoriasis, keloids, and alopecia areata.
• Ophthalmic Treatments: Component in formulations for treating inflammatory eye diseases.
• Veterinary Medicine: Application in anti-inflammatory treatments for animals.
• Research & Development: Serves as a reference standard and key intermediate in pharmacological and clinical research.

Basic Information

Product Name	Triamcinolone Hexacetonide
CAS No.	5611-51-8
Molecular Formula	C30H41FO7
Molecular Weight	532.65 g/mol
Synonyms	Triamcinolone Acetonide 21-(3,3-Dimethylbutyrate); Triamcinolone 16α,17α-Acetonide 21-(3,3-Dimethylbutyrate); Aristospan® (branded form); Hexacetonide Triamcinolone; 9α-Fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone, 21-(3,3-dimethylbutyrate)
EINECS	Contact for details

Quality Control

Our Triamcinolone Hexacetonide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. Certificates of Analysis (COA) are provided, detailing results for identity, purity, and related substances. We can support compliance with relevant pharmacopeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.