Description

(5S,8S,9S,10S,11S,13S,14S,17S)-11,17-Dihydroxy-10,13,17-Trimethyl-2,4,5,6,7,8,9,11,12,14,15,16-Dodecahydro-1H-Cyclopenta[A]Phenanthren-3-One is a high-purity steroidal compound, also known as 5β-Androstane-3,17-dione, serving as a critical intermediate in the synthesis of complex steroid hormones and active pharmaceutical ingredients (APIs). Its defined stereochemistry and structural integrity are essential for ensuring the efficacy and safety of downstream pharmaceutical products. This compound is primarily required by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in steroid chemistry, drug discovery, and process development.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of steroidal drugs, including corticosteroids, anabolic agents, and hormone therapies.
• Research & Development: Used as a reference standard and starting material in medicinal chemistry for exploring new therapeutic compounds and metabolic pathways.
• Biochemical Research: Employed in studies of steroidogenesis, enzyme inhibition assays, and receptor binding studies due to its specific androstane structure.
• Process Chemistry: Serves as a pivotal intermediate in the multi-step industrial-scale manufacturing of complex steroid APIs, where consistent quality is paramount.

Basic Information

Product Name	(5S,8S,9S,10S,11S,13S,14S,17S)-11,17-Dihydroxy-10,13,17-Trimethyl-2,4,5,6,7,8,9,11,12,14,15,16-Dodecahydro-1H-Cyclopenta[A]Phenanthren-3-One
CAS No.	5454-55-7
Molecular Formula	C20H30O3
Molecular Weight	318.45 g/mol
Synonyms	5β-Androstane-3,17-dione; Etiocholane-3,17-dione; 3,17-Dioxo-5β-androstane; 17β-Hydroxy-5β-androstan-3-one; NSC 25247; 5β-Androstanedione; 3,17-Diketocholane
EINECS	226-686-4

Quality Control

Our (5S,8S,9S,10S,11S,13S,14S,17S)-11,17-Dihydroxy-10,13,17-Trimethyl-2,4,5,6,7,8,9,11,12,14,15,16-Dodecahydro-1H-Cyclopenta[A]Phenanthren-3-One is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and conformity to customer specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.