Description

2,3,5,6-Tetrafluorobenzonitrile is a versatile fluorinated aromatic building block, distinguished by its unique substitution pattern. This compound is valued for its role as a key intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and industrial manufacturers in the agrochemical, pharmaceutical, and specialty chemical sectors.

Application

• Agrochemical Intermediates: A critical precursor in the synthesis of novel herbicides and pesticides, leveraging the stability and lipophilicity imparted by the fluorine atoms.
• Pharmaceutical Synthesis: Serves as a key building block for fluorinated drug candidates, particularly in areas like oncology and central nervous system (CNS) therapeutics.
• Liquid Crystal & OLED Materials: Used in the development of fluorinated components for electronic displays and organic light-emitting diodes due to its electronic properties.
• Polymer Modification: Acts as a monomer or modifier to introduce fluorine into polymer backbones, enhancing chemical resistance and thermal stability.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions and as a ligand precursor in organometallic chemistry and catalysis research.
• Advanced Material Research: Utilized in academic and industrial R&D for creating novel fluorinated aromatic systems with tailored properties.

Basic Information

Product Name	2,3,5,6-Tetrafluorobenzonitrile
CAS No.	5216-17-1
Molecular Formula	C7HF4N
Molecular Weight	175.08 g/mol
Synonyms	2,3,5,6-Tetrafluorobenzene carbonitrile; Perfluorobenzonitrile (ambiguous, but commonly searched); 2,3,5,6-Tetrafluorophenyl cyanide; Benzene carbonitrile, 2,3,5,6-tetrafluoro-; TFB (abbreviation); 2,3,5,6-Tetrafluorobenzonitrile; 2,3,5,6-Tetrafluorobenzonitrile; 5216-17-1 (CAS-based synonym)
EINECS	226-025-9

Quality Control

Our 2,3,5,6-Tetrafluorobenzonitrile is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.