Description

Prednisolone Steaglate is a steroidal ester prodrug, specifically the stearic acid ester of prednisolone. This chemical modification is designed to enhance the lipophilicity and potentially alter the pharmacokinetic profile of the parent glucocorticoid. It is primarily utilized in advanced pharmaceutical research and development for creating novel drug delivery systems and formulations. Key industries that require this compound include pharmaceutical manufacturing, contract research organizations (CROs), and academic institutions focused on steroid chemistry and controlled-release therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of specialized corticosteroid prodrugs and active pharmaceutical ingredients (APIs).
• Drug Delivery Research: Investigated for use in lipophilic carrier systems, microspheres, and implants to achieve sustained or targeted release of prednisolone.
• Formulation Development: Used in R&D to improve the solubility, stability, and bioavailability of corticosteroid formulations.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Applied in preclinical studies to explore the metabolism and structure-activity relationships of steroid esters.

Basic Information

Product Name	Prednisolone Steaglate
CAS No.	5060-55-9
Molecular Formula	C39H62O7
Molecular Weight	642.91 g/mol
Synonyms	Prednisolone 21-Stearate; Prednisolone Stearate; 11β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione 21-stearate; NSC 52907; Stearic acid prednisolone ester; Prednisolone 21-(octadecanoate); 17α,21-Dihydroxypregna-1,4-diene-3,11,20-trione 21-stearate
EINECS	225-749-5

Quality Control

Our Prednisolone Steaglate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets high-purity standards suitable for research and development purposes. A Certificate of Analysis (COA) detailing the specific results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.