Description

Nifenalol CAS NO 5054-57-9 is a high-purity pharmaceutical intermediate and research chemical. It serves as a critical building block in the synthesis of advanced active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers requiring reliable, high-quality raw materials for their processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of β-adrenergic blocking agents (β-blockers) and other cardiovascular drugs.
• Organic Synthesis Building Block: Used in research and production for constructing complex molecular architectures, particularly those containing aryloxypropanolamine motifs.
• Biochemical Research: Employed in pharmacological studies to investigate adrenergic receptor activity and related biochemical pathways.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical analysis.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals for agrochemical and material science applications.

Basic Information

Product Name	Nifenalol
CAS No.	5054-57-9
Molecular Formula	C15H16N2O3
Molecular Weight	272.30 g/mol
Synonyms	Nifenalol; INPEA; 4-[2-Hydroxy-3-[(1-methyl-3-phenylpropyl)amino]propoxy]benzonitrile; 1-(4-Cyanophenoxy)-3-[(1-methyl-3-phenylpropyl)amino]-2-propanol; α-[(1-Methyl-3-phenylpropyl)amino]methyl]-4-hydroxybenzenepropanol nitrile ether; Nifenalolum; (±)-Nifenalol
EINECS	Contact for details

Quality Control

Our Nifenalol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) detailing the results of these tests are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.