Description

Pregna-1,4-Diene-3,20-Dione, 11,17-Dihydroxy-6-Methyl-21-(Phosphonooxy)-, Disodium Salt, (6Alpha,11Beta)- is a high-purity, water-soluble corticosteroid phosphate ester salt. This compound is a critical pharmaceutical intermediate and reference standard used in the development and quality control of advanced anti-inflammatory and immunosuppressive medications. It is essential for manufacturers and research institutions in the pharmaceutical and biotechnology sectors requiring precise and reliable steroid chemistry.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of potent topical and systemic corticosteroid drugs.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality assurance in pharmaceutical laboratories.
• Active Pharmaceutical Ingredient (API) Research: Serves as a precursor or model compound in the research and development of new steroid-based therapeutics.
• Biochemical Research: Utilized in studies investigating glucocorticoid receptor binding, anti-inflammatory pathways, and cellular signaling mechanisms.
• Veterinary Medicine: Potential application in the formulation of anti-inflammatory treatments for animals.

Basic Information

Product Name	Pregna-1,4-Diene-3,20-Dione, 11,17-Dihydroxy-6-Methyl-21-(Phosphonooxy)-, Disodium Salt, (6Alpha,11Beta)-
CAS No.	5015-36-1
Molecular Formula	C22H29Na2O8P
Molecular Weight	498.41 g/mol
Synonyms	Methylprednisolone 21-Phosphate Disodium Salt; 6α-Methylprednisolone 21-Phosphate Disodium Salt; U-67590A; Medrate-21-Phosphate Disodium; 11β,17α,21-Trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-(dihydrogen phosphate) disodium salt
EINECS	Contact for details

Quality Control

Our Pregna-1,4-Diene-3,20-Dione, 11,17-Dihydroxy-6-Methyl-21-(Phosphonooxy)-, Disodium Salt, (6Alpha,11Beta)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.