Description

2-(4-Fluorophenyl)-2-(Pyridin-2-Yl)Acetonitrile is a high-value, multi-functional chemical intermediate featuring both a fluorinated phenyl ring and a pyridine moiety. This unique structure makes it a critical building block for the synthesis of complex molecules, particularly in advanced pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom and heterocyclic structure can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers, due to its electron-deficient aromatic systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.

Basic Information

Product Name	2-(4-Fluorophenyl)-2-(Pyridin-2-Yl)Acetonitrile
CAS No.	5005-42-5
Molecular Formula	C₁₃H₉FN₂
Molecular Weight	212.23 g/mol
Synonyms	2-(4-Fluorophenyl)-2-(2-Pyridinyl)acetonitrile; (4-Fluorophenyl)(pyridin-2-yl)acetonitrile; α-(4-Fluorophenyl)-2-pyridineacetonitrile; 2-Pyridyl(4-fluorophenyl)acetonitrile; 5005-42-5; (4-Fluorobenzyl)(pyridin-2-yl)acetonitrile (common misnomer); 2-(4-Fluorophenyl)-2-(2-pyridyl)acetonitrile
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenyl)-2-(Pyridin-2-Yl)Acetonitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and scale-up with custom purity grades, from research (95%+) to high-purity (98%+) standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Research Grade)
Purity (HPLC)	≥ 98.0% (High Purity Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.