Description

18-Hydroxyprogesterone is a key steroid intermediate with significant importance in pharmaceutical synthesis. This compound serves as a crucial precursor in the production of various steroid hormones and active pharmaceutical ingredients (APIs). It is primarily utilized by manufacturers in the pharmaceutical, biotechnology, and fine chemical industries for research, development, and commercial-scale production processes.

Application

• Pharmaceutical Intermediate: A vital building block in the synthesis of corticosteroid and other steroid-based APIs.
• Biochemical Research: Used as a reference standard and reagent in studies of steroid metabolism and endocrine pathways.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules for medicinal chemistry.
• Reference Material: Serves as a high-purity analytical standard for quality control laboratories.

Basic Information

Product Name	18-Hydroxyprogesterone
CAS No.	596-69-0
Molecular Formula	C21H30O3
Molecular Weight	330.46 g/mol
Synonyms	18-Hydroxyprogesterone; 18-OHP; 18-Hydroxy-4-pregnene-3,20-dione; 11-Deoxycorticosterone 18-alcohol; 18-Hydroxypregn-4-ene-3,20-dione; 18-Hydroxyprogestone; 18-OH-Progesterone
EINECS	209-889-2

Quality Control

Our 18-Hydroxyprogesterone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade specifications suitable for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.