Description

14,21-Dihydroxypregn-4-Ene-3,20-Dione is a high-purity steroid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries requiring a reliable, high-quality building block for producing corticosteroids and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of corticosteroid APIs and other steroid-based therapeutics.
• Research & Development: Used in academic and industrial laboratories for studying steroid metabolism, receptor binding, and structure-activity relationships.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create novel steroid analogs with potential biological activity.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	14,21-Dihydroxypregn-4-Ene-3,20-Dione
CAS No.	595-71-1
Molecular Formula	C21H30O4
Molecular Weight	346.46 g/mol
Synonyms	14α,21-Dihydroxypregn-4-ene-3,20-dione; 14α,21-Dihydroxyprogesterone; 14,21-Dihydroxy-4-pregnene-3,20-dione; 14α-Hydroxy-21-hydroxyprogesterone; 14α,21-Dihydroxy-4-pregnene-3,20-dione; 14,21-Dihydroxyprogesterone; 14α,21-Dihydroxypregn-4-en-3,20-dione
EINECS	Contact for details

Quality Control

Our 14,21-Dihydroxypregn-4-Ene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.