Description

2-Chloro-5-(Trifluoromethoxy)Nitrobenzene is a high-purity, multi-functional aromatic intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring chloro, nitro, and trifluoromethoxy substituents, makes it a versatile building block for creating complex molecules with tailored properties. This compound is essential for R&D chemists and production specialists in the agrochemical and pharmaceutical industries seeking to develop novel active ingredients and fine chemicals.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethoxy and nitro groups.
• Pharmaceutical Building Block: Used in medicinal chemistry research for the development of new drug candidates, particularly those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Liquid Crystal & OLED Material Synthesis: Serves as a starting material for creating specialized fluorinated aromatic compounds used in electronic display technologies.
• Dyestuff & Pigment Intermediate: Employed in the production of high-performance, light-fast dyes and pigments.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Chemical Research & Development: A valuable reagent for exploring novel reaction pathways and synthesizing libraries of fluorinated compounds for screening.

Basic Information

Product Name	2-Chloro-5-(Trifluoromethoxy)Nitrobenzene
CAS No.	588-09-0
Molecular Formula	C7H3ClF3NO3
Molecular Weight	241.55 g/mol
Synonyms	1-Chloro-2-nitro-4-(trifluoromethoxy)benzene; 2-Nitro-5-(trifluoromethoxy)chlorobenzene; 2-Chloro-1-nitro-4-(trifluoromethoxy)benzene; 2-Chloro-α,α,α-trifluoro-p-nitroanisole; 4-Chloro-3-(trifluoromethoxy)nitrobenzene; 588-09-0; Benzene, 2-chloro-1-nitro-4-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(Trifluoromethoxy)Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent composition. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.