Description

6-Hydroxycorticosterone is a naturally occurring steroid metabolite and a key intermediate in the biosynthesis of other important corticosteroids. This compound is of significant interest in biochemical research and pharmaceutical development due to its role in steroid hormone pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex steroid-based molecules.

Application

• Biochemical Research: Used as a reference standard and intermediate in studies of corticosteroid biosynthesis, metabolism, and enzymatic pathways.
• Pharmaceutical R&D: Serves as a critical precursor or intermediate in the synthesis and development of novel steroid-based therapeutic agents.
• Metabolite Analysis: Employed as an analytical standard in LC-MS, HPLC, and other chromatographic methods for the quantification of steroid metabolites in biological samples.
• Enzymology Studies: Acts as a substrate for studying the activity and kinetics of hydroxylase and other steroid-modifying enzymes.
• Fine Chemical Synthesis: A valuable building block for the custom synthesis of more complex, high-value steroid derivatives for specialized applications.

Basic Information

Product Name	6-Hydroxycorticosterone
CAS No.	570-25-2
Molecular Formula	C21H30O6
Molecular Weight	378.46 g/mol
Synonyms	6β-Hydroxycorticosterone; 11β,21-Dihydroxy-3,20-dioxopregn-4-en-6β-ol; 6β-Hydroxy-11-dehydrocorticosterone; 6-Hydroxy Reichstein's Substance E; 6β-Hydroxy-17-deoxycortisone; 6β,11β,21-Trihydroxypregn-4-ene-3,20-dione; 6-Hydroxy Compound B
EINECS	Contact for details

Quality Control

Our 6-Hydroxycorticosterone is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.