Description

3-Beta,5-α-Tetrahydrodeosoxycorticosterone is a synthetic steroid derivative of deoxycorticosterone, a key mineralocorticoid hormone precursor. This compound is of significant interest in pharmaceutical research and development, particularly for studying hormone metabolism and receptor interactions. It serves as a critical intermediate and reference standard for laboratories and manufacturers in the pharmaceutical, biotechnology, and life science research sectors.

Application

• Pharmaceutical Intermediate: Used in the synthesis and research of novel steroid-based therapeutics.
• Biochemical Research: Acts as a reference standard and analytical reagent in studies of mineralocorticoid pathways and adrenal cortex function.
• Metabolite Studies: Employed in metabolic and pharmacokinetic research to understand the breakdown pathways of related corticosteroids.
• Endocrinology Research: A key compound for investigating hormone regulation, receptor binding assays, and enzyme inhibition studies.
• Quality Control Standard: Serves as a high-purity certified reference material (CRM) for analytical method development and validation in QC laboratories.

Basic Information

Product Name	3-Beta,5-α-Tetrahydrodeosoxycorticosterone
CAS No.	567-01-1
Molecular Formula	C21H32O3
Molecular Weight	332.48 g/mol
Synonyms	3β,5α-Tetrahydrodeoxycorticosterone; 3β,5α-THDOC; 5α-Pregnan-3β,21-diol-20-one; Allotetrahydrodeoxycorticosterone; 21-Hydroxy-5α-pregnane-3,20-dione; 3β-Hydroxy-5α-pregnan-20-one; NSC 113986
EINECS	209-286-5

Quality Control

Our 3-Beta,5-α-Tetrahydrodeosoxycorticosterone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets high-grade specifications suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.