Description

11-α-Hydrocortisone is a specific stereoisomer of hydrocortisone, a key corticosteroid hormone. This compound is of significant interest in pharmaceutical research and development, particularly for studying structure-activity relationships and metabolic pathways. It serves as a critical intermediate and reference standard for the synthesis and analysis of novel steroidal drugs. Industries requiring high-purity steroid intermediates, such as pharmaceutical R&D, analytical laboratories, and fine chemical synthesis, will find this product essential.

Application

• Pharmaceutical Intermediate: Used in the research and synthesis of novel corticosteroid-based therapeutics.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical testing.
• Biochemical Research: Employed in metabolic studies to understand the activity and transformation of steroid hormones.
• Fine Chemical Synthesis: A key building block for the preparation of more complex, biologically active steroid derivatives.
• Academic Research: Utilized in university and institutional labs for pharmacological and endocrinological studies.

Basic Information

Product Name	11-α-Hydrocortisone
CAS No.	566-35-8
Molecular Formula	C21H30O5
Molecular Weight	362.46 g/mol
Synonyms	11α-Hydroxycortisol; 11α-Hydrocortisone; (11α)-11,17,21-Trihydroxypregn-4-ene-3,20-dione; 11α-HC; 11-epi-Hydrocortisone; Cortisol 11α-isomer
EINECS	Contact for details

Quality Control

Our 11-α-Hydrocortisone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all test results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.