Description

18-Hydroxycorticosterone is a significant steroid hormone and a key intermediate in the biosynthesis of aldosterone. This compound matters for researchers and manufacturers as it provides a crucial building block for studying adrenal cortex function and developing related pharmaceutical compounds. It is primarily needed by the pharmaceutical, biotechnology, and life science research industries for applications in endocrinology, metabolic pathway analysis, and reference standard production.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of aldosterone and other mineralocorticoids.
• Biochemical Research: Used as a reference standard and reagent in studies of steroidogenesis and adrenal gland physiology.
• Endocrinology Studies: Essential for investigating the renin-angiotensin-aldosterone system (RAAS) and related disorders.
• Metabolic Pathway Analysis: Employed to trace and understand the biosynthetic pathways of corticosteroids.
• Diagnostic Development: Utilized in the development and calibration of immunoassays for steroid hormone detection.
• Academic & Contract Research: A key material for universities and CROs conducting advanced hormonal and metabolic research.

Basic Information

Item	Detail
Product Name	18-Hydroxycorticosterone
CAS No.	561-65-9
Molecular Formula	C21H30O5
Molecular Weight	362.46 g/mol
Synonyms	18-Hydroxycorticosterone; 18-OH-Corticosterone; 11β,18,21-Trihydroxypregn-4-ene-3,20-dione; 18-Hydroxy-11-deoxycorticosterone; 18-OH-DOC; 18-Hydroxy Compound B; Reichstein's Substance V
EINECS	Contact for details

Quality Control

Our 18-Hydroxycorticosterone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, IR for identification, and residual solvent analysis to ensure it meets high-purity standards suitable for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.