Description

Propanolol CAS NO 525-66-6 is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) belonging to the class of β-adrenergic blocking agents. This compound is critical for the development and manufacturing of cardiovascular medications, offering reliable performance in synthesis and formulation. It is primarily utilized by pharmaceutical manufacturers, research institutions, and fine chemical suppliers serving the global healthcare sector.

Application

• Pharmaceutical API Synthesis: Core intermediate in the production of β-blocker medications for hypertension and angina.
• Cardiovascular Drug Formulation: Active ingredient used in the development of tablets, capsules, and controlled-release dosage forms.
• Biochemical Research: Reference standard and tool compound for studying adrenergic receptor mechanisms and cardiovascular pharmacology.
• Generic Drug Manufacturing: Essential for producing cost-effective generic versions of established β-blocker therapies.
• Veterinary Medicine: Used in formulations for managing cardiac conditions in animals.
• Academic & Clinical Research: Serves as a key material for pharmacokinetic and metabolic pathway studies.

Basic Information

Product Name	Propanolol
CAS No.	525-66-6
Molecular Formula	C16H21NO2
Molecular Weight	259.34 g/mol
Synonyms	Propranolol; 1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol; (±)-Propranolol; ICI 45520; Avlocardyl; Inderal; Deralin; Dociton; Anaprilin; Betadren; Angilol; Bedranol; Efektolol
EINECS	208-378-2

Quality Control

Our Propanolol is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling. Certificates of Analysis (COA) are provided, confirming compliance with in-house specifications and relevant pharmacopeial guidelines (e.g., USP, EP). We are committed to supply chain transparency and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 99.0%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.