Description

[8S,(-)]-7,10-Dihydro-10-Methyl-8-(1-Methylethyl)-1,3-Dioxolo[4,5-H]Furo[2,3-B]Quinoline-6(8H)-One is a high-purity, complex heterocyclic compound with a defined stereochemistry, serving as a critical intermediate in advanced organic synthesis. Its unique fused ring structure makes it a valuable building block for pharmaceutical research and the development of novel bioactive molecules. This compound is essential for R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new compounds with specific stereochemical and functional properties.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or anti-infective drug candidates.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex natural product analogs and exploring new chemical spaces due to its intricate furoquinoline scaffold.
• Agrochemical Development: Serves as a precursor in the research and development of new pesticides or herbicides, leveraging its heterocyclic core for biological activity.
• Material Science: Investigated as a potential precursor for specialty chemicals, dyes, or ligands in catalytic systems.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in laboratories.

Basic Information

Product Name	[8S,(-)]-7,10-Dihydro-10-Methyl-8-(1-Methylethyl)-1,3-Dioxolo[4,5-H]Furo[2,3-B]Quinoline-6(8H)-One
CAS No.	518-60-5
Molecular Formula	C₁₈H₁₉NO₄
Molecular Weight	313.35 g/mol
Synonyms	(-)-Fagarine; (8S)-Fagarine; L-Fagarine; 8S-Fagarine; 7,10-Dihydro-10-methyl-8-(1-methylethyl)-1,3-dioxolo[4,5-h]furo[2,3-b]quinolin-6(8H)-one; Fagarine; 8-Isopropyl-10-methylfuro[2,3-b]quinolin-6-one 1,3-dioxide (obsolete); Skimmianine isomer
EINECS	Contact for details

Quality Control

Our [8S,(-)]-7,10-Dihydro-10-Methyl-8-(1-Methylethyl)-1,3-Dioxolo[4,5-H]Furo[2,3-B]Quinoline-6(8H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material tailored to specific research or development project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Specific Rotation	Contact for details
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.