Description

Fludrocortisone Acetate is a synthetic corticosteroid with potent mineralocorticoid activity. This high-purity active pharmaceutical ingredient (API) is critical for the formulation of life-sustaining hormone replacement therapies. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of medications for adrenal insufficiency and related endocrine disorders.

Application

• Pharmaceutical API: Primary active ingredient in oral tablets and other formulations for treating Addison's disease and congenital adrenal hyperplasia.
• Mineralocorticoid Replacement Therapy: Essential for managing salt-wasting conditions by regulating sodium and potassium balance in the body.
• Reference Standard: Used in analytical laboratories for quality control, method development, and calibration in HPLC and other chromatographic systems.
• Clinical Research: Serves as a key compound in preclinical and clinical studies investigating corticosteroid pathways and new therapeutic applications.
• Formulation Development: Employed in R&D for developing new drug delivery systems, including controlled-release formulations.

Basic Information

Product Name	Fludrocortisone Acetate
CAS No.	514-36-3
Molecular Formula	C23H31FO6
Molecular Weight	422.49 g/mol
Synonyms	9α-Fluorohydrocortisone Acetate; 9α-Fluoro-11β,17α,21-trihydroxypregn-4-ene-3,20-dione 21-acetate; 9α-Fluorocortisol Acetate; Florinef Acetate; Astonin-H; Alfluorone; Fluodrocortisone Acetate; Fludrocortisoni Acetas
EINECS	208-178-3

Quality Control

Our Fludrocortisone Acetate is manufactured under strict quality management systems. It undergoes comprehensive analytical testing to meet high-purity standards suitable for pharmaceutical applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.