Description

Methylprednisolone Acetate is a synthetic glucocorticoid corticosteroid, widely recognized for its potent anti-inflammatory and immunosuppressive properties. This high-purity active pharmaceutical ingredient (API) is critical for formulating reliable and effective steroidal medications. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of injectable suspensions and topical formulations for treating severe allergic reactions, rheumatic disorders, and certain autoimmune conditions.

Application

• Pharmaceutical API: Core ingredient in injectable depot formulations for prolonged anti-inflammatory and immunosuppressive therapy.
• Rheumatology & Immunology: Treatment of conditions such as rheumatoid arthritis, lupus, and acute gouty arthritis.
• Allergy & Asthma Management: Used in severe allergic reactions and as adjunctive therapy for status asthmaticus.
• Dermatological Preparations: Incorporated into creams and ointments for treating severe skin inflammations like psoriasis and eczema.
• Ophthalmic Solutions: Used in eye drops to treat inflammatory eye conditions.
• Veterinary Medicine: Anti-inflammatory agent in veterinary pharmaceutical products.
• Biomedical Research: Standard compound for studying glucocorticoid receptor activity and steroid pharmacology.

Basic Information

Product Name	Methylprednisolone Acetate
CAS No.	53-36-1
Molecular Formula	C24H32O6
Molecular Weight	416.51 g/mol
Synonyms	6α-Methylprednisolone 21-acetate; Medrol Acetate; Depo-Medrol; 11β,17,21-Trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-acetate; U-67590A; Methylprednisolone 21-acetate; 6α-Methyl-δ1-hydrocortisone acetate
EINECS	200-174-9

Quality Control

Our Methylprednisolone Acetate is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP and EP. Every batch undergoes comprehensive analytical testing including identification, assay, and impurity profiling to ensure high purity and consistent performance. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and quality assurance for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Specific Rotation	+97° to +105°
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Residual Solvents	Complies with ICH Q3C
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.