Description

Aldosterone CAS NO 52-39-1 is a vital mineralocorticoid steroid hormone that plays a central role in regulating electrolyte and water balance within the body. Its precise chemical structure and high purity are critical for reliable research and pharmaceutical development. This compound is essential for manufacturers and researchers in the pharmaceutical, life sciences, and diagnostic industries, particularly for applications in endocrinology, hypertension research, and the development of therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used as a primary standard for the quality control and assay validation of related drug substances and finished products.
• Biochemical Research: A key reagent in studies of the renin-angiotensin-aldosterone system (RAAS), hormone signaling pathways, and renal physiology.
• Diagnostic Kit Manufacturing: Serves as a critical component in the production of immunoassay kits (e.g., ELISA, RIA) for the quantitative measurement of aldosterone in clinical samples.
• Drug Discovery & Development: Employed in high-throughput screening and pharmacological testing for the development of novel mineralocorticoid receptor antagonists and related therapeutics.
• Academic & Clinical Studies: Utilized in university and hospital laboratories to investigate disorders related to electrolyte imbalance, such as Conn's syndrome and heart failure.

Basic Information

Product Name	Aldosterone
CAS No.	52-39-1
Molecular Formula	C21H28O5
Molecular Weight	360.44 g/mol
Synonyms	11β,21-Dihydroxy-3,20-dioxopregn-4-en-18-al; Aldocorten; Electrocortin; 18-Aldocorticosterone; 11β,21-Dihydroxy-18-oxopregn-4-ene-3,20-dione; Reichstein's substance Q
EINECS	200-139-9

Quality Control

Our Aldosterone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and specific tests for related substances, to ensure it meets exacting standards suitable for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.