Description

Prednisoloneacetate CAS NO 51-21-1 is a synthetic glucocorticoid corticosteroid, specifically the 21-acetate ester of prednisolone. This compound is a critical active pharmaceutical ingredient (API) valued for its potent anti-inflammatory and immunosuppressive properties. It is primarily required by pharmaceutical manufacturers for the formulation of ophthalmic suspensions, topical creams, and injectable solutions used to treat severe allergic reactions, inflammatory conditions, and certain autoimmune disorders.

Application

• Ophthalmic Formulations: Key ingredient in eye drops and suspensions for treating uveitis, allergic conjunctivitis, and post-operative inflammation.
• Topical Pharmaceuticals: Used in creams, ointments, and lotions for managing dermatological conditions like eczema, psoriasis, and contact dermatitis.
• Injectable Solutions: Formulated for intramuscular or intra-articular injections to provide rapid relief from severe inflammation and pain.
• Veterinary Medicine: Employed in treatments for inflammatory and allergic conditions in companion and livestock animals.
• Research & Development: Serves as a reference standard and a key intermediate in pharmacological and biochemical research.

Basic Information

Product Name	Prednisoloneacetate
CAS No.	51-21-1
Molecular Formula	C23H30O6
Molecular Weight	402.48 g/mol
Synonyms	Prednisolone 21-Acetate; 11β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione 21-acetate; 1,4-Pregnadiene-11β,17α,21-triol-3,20-dione 21-acetate; δ1-Hydrocortisone acetate; Metacortandralone acetate; NSC-527579; Prednisolone Acetate (USP); Prednisolone Acetate (EP)
EINECS	200-086-3

Quality Control

Our Prednisoloneacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets or exceeds the stringent requirements of major pharmacopoeias, including USP (United States Pharmacopeia) and EP (European Pharmacopoeia) monographs. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	+112° to +122° (c=1 in dioxane)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.