Description

Benzonitrile, 3-Bromo-2,5,6-Trifluoro- CAS NO 485318-78-3 is a high-purity, multi-functional halogenated aromatic nitrile building block. This compound is valued for its unique trifluoro and bromo substitution pattern, which imparts specific electronic and steric properties critical for advanced synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates. Its precise structure makes it an essential reagent for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced bioavailability and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a sophisticated intermediate in the production of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form complex biaryl structures.
• Fluorinated Dye & Pigment Intermediate: Employed in the development of novel fluorinated dyes and pigments with unique color fastness and optical properties.
• Advanced Polymer Research: Acts as a monomer or modifier in the synthesis of high-performance, fluorinated polymers with exceptional chemical and thermal resistance.

Basic Information

Product Name	Benzonitrile, 3-Bromo-2,5,6-Trifluoro-
CAS No.	485318-78-3
Molecular Formula	C7HBrF3N
Molecular Weight	230.00 g/mol
Synonyms	3-Bromo-2,5,6-trifluorobenzonitrile; 2,5,6-Trifluoro-3-bromobenzonitrile; 3-Bromo-2,5,6-trifluorobenzene carbonitrile; Benzonitrile, 3-bromo-2,5,6-trifluoro-; 3-Br-2,5,6-F3-C6HN
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2,5,6-trifluorobenzonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive R&D and scale-up processes. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases, strong oxidizing agents, and strong reducing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.