Description

2-[(4-Methylphenyl)Sulfanyl]-5-(Trifluoromethyl)Benzenecarbonitrile is a high-value, multi-functional chemical intermediate characterized by its benzonitrile core, aryl sulfide linkage, and trifluoromethyl group. This unique structure makes it a critical building block for advanced synthesis, offering significant value in the development of novel compounds with tailored properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to construct complex molecular architectures for various R&D purposes.

Basic Information

Product Name	2-[(4-Methylphenyl)Sulfanyl]-5-(Trifluoromethyl)Benzenecarbonitrile
CAS No.	477867-12-2
Molecular Formula	C15H10F3NS
Molecular Weight	293.31 g/mol
Synonyms	5-(Trifluoromethyl)-2-[(4-methylphenyl)thio]benzonitrile; 2-[(4-Methylphenyl)thio]-5-(trifluoromethyl)benzonitrile; 2-(p-Tolylthio)-5-(trifluoromethyl)benzonitrile; 4'-(Methylthio)-2'-(trifluoromethyl)[1,1'-biphenyl]-4-carbonitrile (related structure); Benzonitrile, 2-[(4-methylphenyl)thio]-5-(trifluoromethyl)-; 477867-12-2
EINECS	Contact for details

Quality Control

Our production of 2-[(4-Methylphenyl)Sulfanyl]-5-(Trifluoromethyl)Benzenecarbonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.