Description

2-[(4-Chlorophenyl)Sulfanyl]-5-(Trifluoromethyl)Benzenecarbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its distinct aryl sulfide and nitrile functional groups. This compound matters for its critical role in the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and fungicides, leveraging the biological activity of the trifluoromethyl and chlorophenyl groups.
• Material Science: Used in the research and development of advanced organic electronic materials and liquid crystals due to its stable aromatic structure.
• Chemical Synthesis: Acts as a versatile synthon for further functionalization, enabling the creation of libraries of compounds for high-throughput screening in drug discovery.

Basic Information

Product Name	2-[(4-Chlorophenyl)Sulfanyl]-5-(Trifluoromethyl)Benzenecarbonitrile
CAS No.	477866-87-8
Molecular Formula	C14H7ClF3NS
Molecular Weight	313.72 g/mol
Synonyms	2-[(4-Chlorophenyl)thio]-5-(trifluoromethyl)benzonitrile; 5-(Trifluoromethyl)-2-[(4-chlorophenyl)thio]benzonitrile; 2-((4-Chlorophenyl)thio)-5-(trifluoromethyl)benzonitrile; Benzonitrile, 2-[(4-chlorophenyl)thio]-5-(trifluoromethyl)-; 2-(4-Chlorophenylsulfanyl)-5-trifluoromethyl-benzonitrile
EINECS	Contact for details

Quality Control

Our production of 2-[(4-Chlorophenyl)Sulfanyl]-5-(Trifluoromethyl)Benzenecarbonitrile adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.