Description

2-Chloro-4-(Trifluoromethyl)Phenylacetonitrile, 97% is a high-purity organic intermediate featuring a versatile nitrile functional group attached to a substituted phenyl ring. This compound matters as a critical building block for synthesizing more complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its specific halogen and trifluoromethyl substitution pattern is highly valuable. It is needed by R&D chemists and process development scientists in fine chemical manufacturing for creating active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Acts as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Functional Dye & Pigment Intermediate: Employed in the manufacture of specialized dyes and pigments with unique colorfastness and chemical resistance properties.
• Cross-Coupling Reactions: The nitrile and aryl chloride functionalities make it a suitable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct complex biaryl systems.
• Organic Synthesis Building Block: Utilized in academic and industrial research labs for the preparation of heterocycles, such as pyrazoles and triazoles, via cyclization reactions.

Basic Information

Product Name	2-Chloro-4-(Trifluoromethyl)Phenylacetonitrile, 97%
CAS No.	474024-26-5
Molecular Formula	C9H5ClF3N
Molecular Weight	219.59 g/mol
Synonyms	2-Chloro-α-(trifluoromethyl)benzeneacetonitrile; (2-Chloro-4-(trifluoromethyl)phenyl)acetonitrile; 2-Chloro-4-trifluoromethylphenylacetonitrile; α-Chloro-α-(trifluoromethyl)benzeneacetonitrile (isomer); 2-Chloro-4-(trifluoromethyl)benzenecetonitrile; 2-Chloro-α,α,α-trifluoro-p-toluacetonitrile; 4-Trifluoromethyl-2-chlorophenylacetonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(Trifluoromethyl)Phenylacetonitrile, 97% undergoes rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed using advanced chromatographic and spectroscopic techniques to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider using an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.