Description

Benzene, 1,2-Difluoro-5-Methyl-3-Nitro- is a high-purity, multi-functional aromatic building block characterized by its unique substitution pattern of fluorine, methyl, and nitro groups. This compound is of significant value in advanced organic synthesis, particularly for the development of complex molecules where precise electronic and steric properties are required. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors, enabling the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced electronic materials, contributing to the molecular framework of dyes, pigments, and charge-transport layers in display technologies.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific properties such as chemical resistance, thermal stability, or altered refractive index.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in organic chemistry, facilitating studies in cross-coupling reactions, nucleophilic aromatic substitution, and structure-activity relationships.

Basic Information

Product Name	Benzene, 1,2-Difluoro-5-Methyl-3-Nitro-
CAS No.	468718-05-0
Molecular Formula	C7H5F2NO2
Molecular Weight	173.12 g/mol
Synonyms	1,2-Difluoro-5-methyl-3-nitrobenzene; 3-Nitro-1,2-difluoro-5-methylbenzene; 5-Methyl-1,2-difluoro-3-nitrobenzene; 2,3-Difluoro-6-nitrotoluene; 1-Methyl-2,3-difluoro-5-nitrobenzene; 468718-05-0; 3-Nitro-5-methyl-1,2-difluorobenzene
EINECS	Contact for details

Quality Control

Our Benzene, 1,2-Difluoro-5-Methyl-3-Nitro- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.