Description

3'-Bromo-5'-Fluorobiphenyl-2-Carbonitrile is a high-purity, multi-functional biphenyl derivative designed for advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and organic building block for constructing complex molecular architectures. It is essential for research and development teams in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging the halogenated biphenyl core for bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Ligand & Catalyst Development: Employed in organometallic chemistry for the creation of novel ligands and catalysts used in cross-coupling reactions.
• Academic & Industrial R&D: A versatile reagent for methodological studies in organic chemistry, including Suzuki-Miyaura and Buchwald-Hartwig amination reactions.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and dyes.

Basic Information

Product Name	3'-Bromo-5'-Fluorobiphenyl-2-Carbonitrile
CAS No.	462652-01-3
Molecular Formula	C13H7BrFN
Molecular Weight	276.11 g/mol
Synonyms	2-Cyano-3'-bromo-5'-fluorobiphenyl; [1,1'-Biphenyl]-2-carbonitrile, 3'-bromo-5'-fluoro-; 3'-Bromo-5'-fluoro-[1,1'-biphenyl]-2-carbonitrile; 3'-Bromo-5'-fluorobiphenyl-2-carbonitrile; 2-(3-Bromo-5-fluorophenyl)benzonitrile; 3-Bromo-5-fluoro-2-cyanobiphenyl
EINECS	Contact for details

Quality Control

Our 3'-Bromo-5'-Fluorobiphenyl-2-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.