Description

4-Bromo-2-Fluoro-6-Methoxybenzonitrile is a high-purity, multi-functional halogenated aromatic nitrile building block. This compound is valued for its unique molecular architecture, which enables precise structural modifications in advanced synthetic pathways. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery and development, particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the bromo and fluoro substituents contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers due to its electron-withdrawing nitrile group and halogen atoms.
• Custom Synthesis & Contract Manufacturing: An essential building block for custom chemical synthesis (CRAMS) providers serving the global life sciences market.

Basic Information

Product Name	4-Bromo-2-Fluoro-6-Methoxybenzonitrile
CAS No.	457051-15-9
Molecular Formula	C8H5BrFNO
Molecular Weight	230.04 g/mol
Synonyms	2-Fluoro-4-bromo-6-methoxybenzonitrile; 6-Methoxy-4-bromo-2-fluorobenzonitrile; Benzonitrile, 4-bromo-2-fluoro-6-methoxy-; 4-Bromo-2-fluoro-6-methoxy-benzonitrile; 457051-15-9
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-Fluoro-6-Methoxybenzonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.