Description

4-[3-(Trifluoromethyl)Phenoxy]Benzenecarbonitrile is a high-value, multi-functional aromatic nitrile derivative featuring a trifluoromethylphenoxy substituent. This compound is a critical advanced pharmaceutical intermediate and agrochemical building block, prized for its ability to impart metabolic stability and lipophilicity to target molecules. It is primarily utilized by R&D and production teams in the pharmaceutical, crop protection, and specialty chemical industries for synthesizing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of small molecule drugs, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl and nitrile groups.
• Liquid Crystal Materials: Used in the research and production of advanced liquid crystal compounds for display technologies.
• Organic Electronic Materials: Serves as a precursor in the synthesis of electron-transport materials for OLEDs and other organic semiconductors.
• Polymer Modification: Functional monomer for creating specialty polymers with enhanced chemical resistance and specific optical properties.
• Chemical Research & Development: Versatile scaffold for medicinal chemistry and material science research programs.

Basic Information

Product Name	4-[3-(Trifluoromethyl)Phenoxy]Benzenecarbonitrile
CAS No.	453557-46-5
Molecular Formula	C14H8F3NO
Molecular Weight	263.22 g/mol
Synonyms	4-[3-(Trifluoromethyl)phenoxy]benzonitrile; [3-(Trifluoromethyl)phenoxy]-4-benzonitrile; 4-(α,α,α-Trifluoro-m-tolyloxy)benzonitrile; 4-(3-Trifluoromethylphenoxy)benzonitrile; Benzonitrile, 4-[3-(trifluoromethyl)phenoxy]-; 4-(3-Trifluoromethyl-phenoxy)-benzonitrile; m-Trifluoromethylphenyl 4-cyanophenyl ether
EINECS	Contact for details

Quality Control

Our 4-[3-(Trifluoromethyl)Phenoxy]Benzenecarbonitrile is manufactured under a cGMP-compliant quality management system, ensuring batch-to-batch consistency for critical applications. Products undergo rigorous quality testing to ensure compliance with industry standards. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.