Description

Methyl 2-Deoxy-2-Fluoro-L-Arabinofuranoside is a high-purity fluorinated carbohydrate derivative, serving as a critical chiral building block and synthetic intermediate. Its value lies in the strategic introduction of a fluorine atom into the sugar scaffold, which can significantly alter biological activity, metabolic stability, and physicochemical properties. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for the synthesis of novel nucleoside analogs, antiviral agents, and diagnostic probes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated nucleoside analogs for antiviral and anticancer drug discovery.
• Antiviral Pro-drug Development: Used to create modified sugar moieties that enhance the bioavailability and efficacy of nucleotide-based therapeutics.
• PET (Positron Emission Tomography) Tracer Synthesis: Acts as a building block for 18F-labeled radiopharmaceuticals used in medical imaging.
• Glycobiology Research: A valuable tool for studying enzyme mechanisms and metabolic pathways involving fluorosugars.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies by probing the role of specific hydroxyl groups in bioactive molecules.
• Process Chemistry & Scale-up: Serves as a starting material for the GMP-compliant production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Methyl 2-Deoxy-2-Fluoro-L-Arabinofuranoside
CAS No.	442514-57-0
Molecular Formula	C6H11FO4
Molecular Weight	166.15 g/mol
Synonyms	Methyl 2-Deoxy-2-fluoro-α-L-arabinofuranoside; 2-Deoxy-2-fluoro-L-arabinofuranose methyl glycoside; Methyl 2-fluoro-2-deoxy-α-L-arabinofuranoside; 1-O-Methyl-2-deoxy-2-fluoro-α-L-arabinofuranose; 2-Fluoro-2-deoxy-L-arabinose methyl glycoside; α-L-Methyl 2-deoxy-2-fluororabinofuranoside
EINECS	Contact for details

Quality Control

Our Methyl 2-Deoxy-2-Fluoro-L-Arabinofuranoside is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and NMR for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.