Description

4-(Dibromomethyl)-2-Fluorobenzonitrile is a versatile and highly functionalized aromatic building block. Its unique structure, featuring both bromomethyl and nitrile groups on a fluorinated benzene ring, makes it a critical intermediate for advanced organic synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require precise molecular scaffolds for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules, particularly those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the dibromomethyl group offers a reactive handle for further functionalization.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functional polymers and advanced organic materials with specific electronic or optical properties.
• Cross-Coupling Reactions: The bromine atoms make it a suitable substrate for various palladium-catalyzed cross-coupling reactions, such as Suzuki or Negishi couplings, to construct complex biaryl structures.

Basic Information

Product Name	4-(Dibromomethyl)-2-Fluorobenzonitrile
CAS No.	440105-58-8
Molecular Formula	C8H4Br2FN
Molecular Weight	292.93 g/mol
Synonyms	2-Fluoro-4-(dibromomethyl)benzonitrile; 4-(Dibromomethyl)-2-fluorobenzonitrile; Benzonitrile, 4-(dibromomethyl)-2-fluoro-; 2-Fluoro-α,α-dibromo-p-tolunitrile; p-Cyano-α,α-dibromo-o-fluorotoluene
EINECS	Contact for details

Quality Control

Our 4-(Dibromomethyl)-2-Fluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.