Description

Benzonitrile, 2-Fluoro-3-Hydroxy-6-Methoxy- (9Ci) is a high-purity, multi-functional aromatic nitrile derivative, distinguished by its specific pattern of fluorine, hydroxyl, and methoxy substituents. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block for the synthesis of complex organic molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require precise molecular architecture for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the fluorine and nitrile groups contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Acts as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional polymers, liquid crystals, and organic electronic materials due to its polar and modifiable structure.
• Chemical Biology Probes: Utilized in the design of fluorescent tags and molecular probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring fluorinated benzonitrile chemistry.

Basic Information

Product Name	Benzonitrile, 2-Fluoro-3-Hydroxy-6-Methoxy- (9Ci)
CAS No.	438497-15-5
Molecular Formula	C8H6FNO2
Molecular Weight	167.14 g/mol
Synonyms	2-Fluoro-3-hydroxy-6-methoxybenzonitrile; 3-Cyano-2-fluoro-6-methoxyphenol; 6-Methoxy-2-fluoro-3-hydroxybenzonitrile; 2-Fluoro-6-methoxy-3-hydroxybenzonitrile; 3-Hydroxy-2-fluoro-6-methoxybenzonitrile; 438497-15-5; 2-Fluoro-3-hydroxy-6-methoxybenzenecarbonitrile
EINECS	Contact for details

Quality Control

Our production of Benzonitrile, 2-Fluoro-3-Hydroxy-6-Methoxy- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support compliance with ICH guidelines and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to strong bases and fluorides; keep away from incompatible materials. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.