Description

2-Bromo-3-Fluorobenzonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents adjacent to a reactive cyano group, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by manufacturers of specialty materials and liquid crystals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Electronics: Employed in the synthesis of conjugated polymers and molecular components for organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form new carbon-carbon bonds.
• Chemical Research: A valuable reagent for academic and industrial R&D in exploring new heterocyclic compounds and fluorinated aromatic systems.

Basic Information

Product Name	2-Bromo-3-Fluorobenzonitrile
CAS No.	425379-16-4
Molecular Formula	C7H3BrFN
Molecular Weight	200.01 g/mol
Synonyms	3-Fluoro-2-bromobenzonitrile; 2-Bromo-3-fluorobenzene carbonitrile; 2-Bromo-3-fluorophenyl cyanide; Benzonitrile, 2-bromo-3-fluoro-; (2-Bromo-3-fluorophenyl)carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Fluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our customers' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.