Description

5'-Bromo-2'-Fluorobiphenyl-2-Carbonitrile is a high-purity, multi-functional biphenyl derivative of significant importance in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of complex molecules. It is primarily utilized by research institutions and chemical manufacturers in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging its halogenated biphenyl structure.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.
• Ligand & Catalyst Development: Employed in the design and synthesis of novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Research: A valuable reagent for academic and industrial R&D in organic and medicinal chemistry for structure-activity relationship (SAR) studies.

Basic Information

Product Name	5'-Bromo-2'-Fluorobiphenyl-2-Carbonitrile
CAS No.	425378-71-8
Molecular Formula	C₁₃H₇BrFN
Molecular Weight	276.11 g/mol
Synonyms	2'-Fluoro-5'-bromobiphenyl-2-carbonitrile; [1,1'-Biphenyl]-2-carbonitrile, 5'-bromo-2'-fluoro-; 5'-Bromo-2'-fluorobiphenyl-2-carbonitrile; 2-Cyano-5'-bromo-2'-fluorobiphenyl; 5'-Bromo-2'-fluoro[1,1'-biphenyl]-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 5'-Bromo-2'-Fluorobiphenyl-2-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.