Description

2-Fluoro-4-(Methylsulfonyl)Benzonitrile is a high-purity, multi-functional organic intermediate featuring a unique combination of fluorine, sulfone, and nitrile functional groups. This compound is valued for its role in facilitating complex molecular transformations and introducing key structural motifs in advanced synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and fine chemicals. Its specific reactivity profile makes it a critical building block for medicinal chemistry and material science applications.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing the methylsulfonyl and fluorobenzonitrile pharmacophores.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its structural elements contribute to biological activity and environmental stability.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing properties.
• Chemical Research & Development: Employed in organic synthesis laboratories for cross-coupling reactions, nucleophilic substitutions, and as a scaffold for constructing complex heterocyclic compounds.
• Fine Chemical Production: Utilized in the custom synthesis of complex, high-value molecules for various industrial and research applications.

Basic Information

Product Name	2-Fluoro-4-(Methylsulfonyl)Benzonitrile
CAS No.	411233-40-4
Molecular Formula	C8H6FNO2S
Molecular Weight	199.20 g/mol
Synonyms	4-(Methylsulfonyl)-2-fluorobenzonitrile; 2-Fluoro-4-methanesulfonylbenzonitrile; 4-Cyano-3-fluorophenyl methyl sulfone; 2-Fluoro-4-(methylsulphonyl)benzonitrile; 411233-40-4; Benzonitrile, 2-fluoro-4-(methylsulfonyl)-; 2-Fluoro-4-methylsulfonylbenzonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-(Methylsulfonyl)Benzonitrile is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We guarantee high chemical purity and consistency to meet the stringent requirements of advanced synthetic applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to ensure full traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.