Description

7β-Fulvestrant CAS NO 407577-53-1 is a high-purity, steroidal active pharmaceutical ingredient (API) and a key chemical intermediate. This compound is critical for pharmaceutical research and development, particularly in the field of endocrinology and hormone-related therapies. It is primarily utilized by pharmaceutical manufacturers and advanced research institutions engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of steroidal drugs and active pharmaceutical ingredients (APIs).
• Biomedical Research: Used as a reference standard and research chemical in studies related to estrogen receptor biology and signaling pathways.
• Drug Discovery & Development: Employed in preclinical research for the development of new hormonal therapies and targeted cancer treatments.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for investigative studies in biochemistry and pharmacology.
• Analytical Standard: Acts as a high-purity standard for quality control and method validation in analytical laboratories (HPLC, LC-MS).

Basic Information

Product Name	7β-Fulvestrant
CAS No.	407577-53-1
Molecular Formula	C32H47F5O3S
Molecular Weight	606.78 g/mol
Synonyms	Fulvestrant 7β-isomer; ICI 182,780 7β-isomer; 7β-Faslodex; (7β,17β)-7-{9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl}estra-1,3,5(10)-triene-3,17-diol; ZD9238 7β-isomer; 7β-Hydroxyfulvestrant; Estrogen receptor antagonist 7β
EINECS	Contact for details

Quality Control

Our 7β-Fulvestrant is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant use and inert atmosphere packing.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.