Description

1H-Imidazo[4,5-C]Pyridine, 4,6,7-Trifluoro- (9Ci) is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique imidazopyridine scaffold and fluorine substitution pattern enable precise modulation of biological activity and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the fluorine atoms.
• Ligand & Catalyst Development: Serves as a sophisticated backbone for designing novel ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLED emitters or charge-transport molecules, due to its electron-deficient heterocyclic structure.
• Chemical Biology Probes: Utilized as a core structure for developing fluorescent tags or molecular probes to study biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthesis projects requiring high-fidelity fluorinated heterocycles.

Basic Information

Product Name	1H-Imidazo[4,5-C]Pyridine, 4,6,7-Trifluoro- (9Ci)
CAS No.	405230-95-7
Molecular Formula	C6H2F3N3
Molecular Weight	173.10 g/mol
Synonyms	4,6,7-Trifluoro-1H-imidazo[4,5-c]pyridine; 4,6,7-Trifluoroimidazo[4,5-c]pyridine; 1H-Imidazo[4,5-c]pyridine, 4,6,7-trifluoro-; 405230-95-7; AI3-40931; AKOS005258495; BDBM50389353; SCHEMBL15524511; ZINC000253909011
EINECS	Contact for details

Quality Control

Our 1H-Imidazo[4,5-C]Pyridine, 4,6,7-Trifluoro- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding R&D and scale-up applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements, including custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is sensitive to light and strong bases; ensure proper handling to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.