Description

21-Deoxyaldosterone is a key intermediate and reference standard in steroid hormone research and pharmaceutical development. This compound is of significant interest for its role in the biosynthesis and metabolic pathways of mineralocorticoids, particularly aldosterone. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in endocrinology studies, analytical method development, and the synthesis of more complex steroid molecules.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis (HPLC, GC-MS) of aldosterone and related steroid metabolites in research and quality control laboratories.
• Biochemical Research: Serves as a critical intermediate or inhibitor in studies investigating the renin-angiotensin-aldosterone system (RAAS), blood pressure regulation, and electrolyte balance.
• Organic Synthesis: Acts as a valuable building block for the chemical synthesis of novel steroid derivatives and potential drug candidates targeting hormone receptors.
• Diagnostic Development: Employed in the development and calibration of immunoassays and other diagnostic kits for measuring aldosterone levels in clinical samples.
• Metabolite Studies: Essential for investigating the metabolic fate and pharmacokinetics of aldosterone and similar therapeutic agents.

Basic Information

Product Name	21-Deoxyaldosterone
CAS No.	47417-48-1
Molecular Formula	C21H28O4
Molecular Weight	344.45 g/mol
Synonyms	21-Desoxyaldosterone; 11β,21-Dihydroxy-3,20-dioxopregn-4-en-18-al; 18-Formyl-11β,21-dihydroxypregn-4-ene-3,20-dione; Aldosterone 21-deoxy; 21-Deoxyaldosterone; 11β,21-Dihydroxypregn-4-ene-3,20-dione-18-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 21-Deoxyaldosterone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for residual solvents and related substances. A Certificate of Analysis (COA) detailing all specifications and results is provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.